Vinorelbine (Navelbine®)

How does this drug work?

Navelbine is a "chemotherapy" drug that prevents cancer cell division and may also injure normal cells which grow fast such as blood cells, hair, cells that line the mouth, stomach, and intestines. It is known as a "vinca" type of chemotherapy and inhibits the cell spindle which is necessary for cell division and growth.

Common side effects

• Lower numbers of white blood cells (which fight against infection), red blood cells (which carry oxygen), platelets (which helps blood clot). A low number of these cells may lead to infection and bleeding

• Skin damage may occur to the area in which Navelbine is given, if the drug leaks out of the vein into the tissue

• Constipation

• Hair thinning

• Numbness, tingling or weakness in hands or feet

• Fatigue or tiredness

• Temporary soreness of the shoulders, back, and thigh (known as myalgia) may occur.

Less common side effects with your type of chemotherapy:

• Nausea, vomiting

As with any drug, other side effects that were not mentioned may occur

General concerns

• Report vomiting or severe nausea lasting more than 1 day

• Immediately report any fevers of 101ƒ or higher, with or without chills

• Report nose bleeds, gum bleeding, or any unusual bruising

• Ask your doctor about a birth control method for you

• Report any symptoms which are unusual for you

Other concerns with your type of chemotherapy

• Report to the nurse immediately any redness, swelling, or discomfort along the injection site

• To prevent constipation, eat high fiber foods such as whole-grain cereal, bran, raw vegetables, and fruits. Drink plenty of fluids. Take a stool softener as needed. Ask your nurse about additional medications to prevent constipation