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Guide Glossary
 Medical Oncology

HER2/neu antibody (RhuMAbHER2)

How does this drug work?

HER2/neu antibody is an experimental antibody drug that binds the HER2/neu protein, a substance on some cancer cells that can help cell grow abnormally. It is being tested in women whose tumors make HER2/neu (about one-fifth of all women with breast cancer). HER2/neu antibody is given by vein every week either alone or with chemotherapy in clinical trials available in certain sites


Common side effects
HER2/neu is usually well tolerated

Less common side effects with your type of chemotherapy:

  • Chills, fever

  • Nausea, vomiting

  • Chest pain

As with any drug, other side effects that were not mentioned may occur


General concerns

  • Report vomiting or severe nausea lasting more than 1 day

  • Immediately report any fevers of 101ƒ or higher, with or without chills

  • Ask your doctor about a birth control method for you

  • Report any symptoms which are unusual for you


During the day, you may reach a doctor or nurse by calling the Breast Care Center Oncology/Chemotherapy number (see phone list).

After hours and on weekends, please be sure to use the specified Oncology/Chemotherapy, as this is the ONLY number to connect you to the appropriate physician on call.